Ivabradine, sold under the brand name Procoralan among others, is a medication used for the symptomatic management of stable heart-related chest pain and heart failure not fully managed by beta blockers.
Ivabradine acts by allowing negative chronotropy in the sinoatrial structure thus reducing the heart rate via specific inhibition of the pacemaker current, a mechanism different from that of beta blockers and calcium channel blockers, two commonly prescribed antianginal classes of cardiac pharmaceuticals. Ivabradine has no apparent inotropic properties and may be a cardiotonic agent.